Ovarian Cancer Immunology

Scientists at Ludwig-Maximilians University target ovarian cancer immunology

Published in Women's Health Weekly, March 5th, 2009

Research findings, 'Immunohistochemistry, glycosylation and immunosuppression of glycodelin in human ovarian cancer,' are discussed in a new report. According to recent research from Munich, Germany, "Glycodelins (Gds) are glycoproteins with a gender specific glycosylation. Glycodelin A (GdA) is primarily produced in endometrial and decidual tissue and secreted to amniotic fluid."

"Glycodelins were also identified in several cancer types, including serous ovarian cancer. Gds act as a T-cell inhibitor and are involved in inactivation of human monocytes. With a Gd peptide antibody, derived from a 15 amino acid sequence of human Gd and in situ hybridization experiments,...

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Source: Women's Health Weekly (2009-03-05)

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