Women's Health Weekly
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Apoptosis
Study findings from University of California broaden understanding of apoptosis
March 5th, 2009
According to a study from the United States, "The intrinsic damage response is activated by DNA damage that arises during the cell division process. The ability of the cell to repair this damage during proliferation is important for normal cell growth and, when disrupted, may lead to increased mutatagenesis and tumorigenesis." "The atypical CDK activator, Spy1, was previously shown to promote cell survival, prevent apoptosis and inhibit checkpoint activation in response to DNA damage. Prior studies have shown that Spy1 is upregulated in breast carcinomas and accelerates mammary tumorigenesis in vivo. In this report, first, we demonstrate that the ability of Spy1 to...
Source: Women's Health Weekly (2009-03-05)
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