Women's Health Weekly
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Breast Cancer
Data from M. Ohara et al provide new insights into breast cancer
March 12th, 2009
According to recent research from Matsushima, Japan, "The FOXP3 mRNA expression and the other regulatory T cell-related molecules were investigated and compared with clinicopathological parameters in human primary breast cancer. This study included 136 breast cancer patients operated in our department from 2003 to 2006." "Total RNA was extracted from frozen normal breast and breast cancer tissues, and the expression of FOXP3, IL-10, TGF beta 1 and CCL22 mRNA was evaluated using quantitative real-time RT-PCR. FOXP3, IL-10, TGF beta 1 and CCL22 mRNA expressions were significantly higher in cancer tissue than in normal tissue, not only at pT1, 2, and 3 stages but also at...
Source: Women's Health Weekly (2009-03-12)
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