Women's Health Weekly
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Breast Cancer
New breast cancer research from K.S. Park and co-researchers described
March 12th, 2009
According to recent research from South Korea, "Activation of NF-kappa B is reported in breast cancers. NF-kappa b inhibition in breast cancer cell lines results in an increase in apoptosis." "However, the reason for continuous activation of this transcription factor in breast cancer is currently unclear. Interestingly, elevated transglutaminase 2 (TGase 2) expression is additionally observed in breast cancer. Recent studies showed that doxorubicin-resistant cells contain a higher level of TGase 2, compared to doxorubicin-sensitive cells. Moreover, increasing the level of TGase 2 in breast cancer cells by transient transfection leads to decreased expression of the...
Source: Women's Health Weekly (2009-03-12)
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