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Women's Health Weekly

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Breast Cancer



Recent studies from University of Keele add new data to breast cancer



March 19th, 2009

According to recent research published in the journal Oncogene, "Effective control of both cell survival and cell proliferation is critical to the prevention of oncogenesis and to successful cancer therapy. Using functional expression cloning, we have identified GAS5 ( growth arrest-specific transcript 5) as critical to the control of mammalian apoptosis and cell population growth."

"GAS5 transcripts are subject to complex post-transcriptional processing and some, but not all, GAS5 transcripts sensitize mammalian cells to apoptosis inducers. We have found that, in some cell lines, GAS5 expression induces growth arrest and apoptosis independently of other stimuli....


Source: Women's Health Weekly (2009-03-19)

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