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Women's Health Weekly

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Ductal Carcinoma in Situ



Researchers from Harvard University report recent findings in ductal carcinoma in situ



March 19th, 2009

"Recent molecular Studies have indicated that ductal carcinoma in situ (DCIS)-associated myoepithelial cells (MECs) show differences from MECs in normal breast tissue. Such alterations may influence the progression of DCIS to invasive cancer," scientists writing in the American Journal of Surgical Pathology report.

"The purpose of this study was to investigate further phenotypic alterations in DCIS-associated MECs. Paraffin sections of 101 cases of DCIS (56 without and 45 with associated invasive carcinoma) were immunostained for 7 MEC markers: smooth muscle actin, smooth muscle myosin heavy chain (SMMHC), calponin, p63, cytokeratin (CK) 5/6, CD10, and p75. In...


Source: Women's Health Weekly (2009-03-19)

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