Women's Health Weekly
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Angiogenesis
Research on angiogenesis published by scientists at Tufts University
March 26th, 2009
"Tumor dormancy has important implications for early detection and treatment of cancer. Lack of experimental models and limited clinical accessibility constitute major obstacles to the molecular characterization of dormant tumors," scientists in the United States report. "We have developed models in which human tumors remain dormant for a prolonged period of time (>120 days) until they switch to rapid growth and become strongly angiogenic. These angiogenic tumors retain their ability to grow fast once injected in new mice. We hypothesized that dormant tumors undergo a stable genetic reprogramming during their switch to the fast-growing phenotype. Genome-wide...
Source: Women's Health Weekly (2009-03-26)
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