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Women's Health Weekly

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Angiogenesis



Scientists at Columbus Children's Hospital target angiogenesis



March 26th, 2009

According to recent research from the United States, "Women with Down syndrome very rarely develop breast cancer even though they now live to an age when it normally occurs. This may be related to the fact that Down syndrome persons have an additional copy of chromosome 21 where the gene that codes for the antiangiogenic protein Endostatin is located."

"Can this information lead to a primary antiangiogenic therapy for early stage breast cancer that indefinitely prolongs remission' A key question that arises is when is the initial angiogenic switch thrown in micrometastases' We have conjectured that avascular micrometastases are dormant and relatively stable if...


Source: Women's Health Weekly (2009-03-26)

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