Women's Health Weekly
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Breast Cancer
Reports from Stanford University advance knowledge in breast cancer
March 26th, 2009
According to recent research from the United States, "Macrophages play an important role in breast carcinogenesis. The pathways that mediate the macrophage contribution to breast cancer and the heterogeneity that exists within macrophages are incompletely understood." "Macrophage colony-stimulating factor 1 (CSF1) is the primary regulator of tissue macrophages. The purpose of this study was to define a novel CSF1 response signature and to evaluate its clinical and biological significance in breast cancer. We defined the CSF1 response signature by identifying genes over-expressed in tenosynovial giant cell tumor and pigmented villonodular synovitis (tumors composed...
Source: Women's Health Weekly (2009-03-26)
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