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Women's Health Weekly

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Breast Cancer



Research reports on breast cancer from L.N. Zhang and colleagues provide new insights



March 26th, 2009

According to recent research from Tianjin, People's Republic of China, "Estrogen plays a role in breast cancer development, and genetic polymorphisms in estrogen receptor gene ER-alpha and genes regulating estrogen biosynthesis and metabolisms are associated with the risk of breast cancer in women in western countries. Therefore, we hypothesized that SNPs in ER-alpha and other estrogen-metabolizing genes contribute to breast cancer risk in Chinese women."

"In this study, we genotyped polymorphisms in the regulatory regions of ER-alpha (rs3798577) and other two estrogen-metabolizing enzyme genes CYP17 (rs743572) and CYP19 (rs10046) among 300 breast cancer cases and 390...


Source: Women's Health Weekly (2009-03-26)

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