Women's Health Weekly
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Breast Cancer
Recent findings in breast cancer described by researchers from Tohoku University
April 2nd, 2009
"17 beta-Hydroxysteroid dehydrogenase type 12 (17 beta-HSD12) has been shown to be involved in elongation of very long chain fatty acid (VLCFA) as well as in biosynthesis of estradiol (E2). 17 beta-HSD12 expression was also reported in breast carcinomas but its functions have remained unknown. In this study, we examined the correlation between mRNA expression profiles determined by microarray analysis and tissue E2 concentrations obtained from 16 postmenopausal breast carcinoma cases," scientists in Sendai, Japan report. "No significant correlations were detected between 17 beta-HSD12 expression and E2 concentration. We then immunolocalized this enzyme in 110 cases of...
Source: Women's Health Weekly (2009-04-02)
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