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Women's Health Weekly

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Breast Cancer



Research from University of Lille provides new data about breast cancer



April 2nd, 2009

According to recent research from France, "We have used a combination of SIDS-PAGE and LTQ-Orbitrap MS to explore the proteome of the highly invasive MDA-MB-231 breast cancer cell line."

"Based on about 520000 MS/MS spectra, a total of 3481 proteins were identified and subsequently classified according to their cellular distribution and molecular function. Interestingly, a large proportion of proteins (38%) were from cellular membranes and we were able to characterize numerous proteins involved in cancer initiation and progression such as the tumor suppressor p53 and the epidermal growth factor receptor," wrote V. Strande and colleagues, University of Lille.

...


Source: Women's Health Weekly (2009-04-02)

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