Women's Health Weekly
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Cancer
New cancer study findings have been reported by scientists at University of Michigan
April 2nd, 2009
According to recent research published in the journal Proteomics Clinical Applications, "An analysis of phosphorylation changes that occur during cancer progression would provide insights into the molecular pathways responsible for a malignant phenotype. In this study we employed a novel coupling of 2-D liquid separations and protein microarray technology to reveal changes in phosphoprotein status between premalignant (ATI) and malignant (CA1a) cell lines derived from the human MCF10A breast cell lines. intact proteins were first separated according to their pi and hydrophobicities, then arrayed on SuperAmine glass slides." "Phosphoproteins were detected using...
Source: Women's Health Weekly (2009-04-02)
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