Women's Health Weekly
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Cancer
Research from Harvard University yields new findings on cancer
April 2nd, 2009
According to a study from the United States, "Female BRCA1 mutation carriers have a nearly 80% probability of developing breast cancer during their life-lime. We hypothesized that the breast epithelium at, risk in BRCA1 mutation carriers harbors mammary epithelial cells (MEC) with altered proliferation and differentiation properties." "Using a three-dimensional culture technique to grow MECs ex vivo, we found that the ability to form colonies, an indication of clonality. was restricted to the aldehyde dehydrogenase 1-positive fraction in MECs but not in HCC1937 BRCA1-mutant cancer cells. primary MECs from BRCA1 mutation carriers (n = 9) had a 28% greater ability for...
Source: Women's Health Weekly (2009-04-02)
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