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Women's Health Weekly

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Chlamydia



New findings in chlamydia described by D. Prantner and co-researchers



April 2nd, 2009

According to a study from the United States, "In many important human pathogens, such as Shigella and Salmonella spp., the bacterial type III secretion (T3S) apparatus is required to initiate inflammation via activation of caspase-1- or NF-kappa B-dependent genes. Using an ex vivo infection model, the goal of the present study was to determine whether the chlamydial T3S apparatus also modulates the host inflammatory response."

"Infections of mouse peritoneal macrophages were performed with Chlamydia muridarum, and the expression of inflammatory cytokines was monitored by quantitative reverse transcription-PCR and enzyme-linked immunosorbent assay. Since there is no...


Source: Women's Health Weekly (2009-04-02)

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