Women's Health Weekly
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Chlamydia
New findings in chlamydia described from University of British Columbia
April 2nd, 2009
According to recent research from Vancouver, Canada, "Using a combination of affinity chromatography and tandem mass spectrometry, we recently identified 8 MHC class II (I-A(b)) -bound Chlamydia peptides eluted from dendritic cells (DCs) infected with Chlamydia muridarum. In this study we cloned and purified the source proteins that contained each of these peptides and determined that three of the eight peptide/protein Ags were immunodominant (PmpG-1, RpIF, and PmpE/F-2) as identified by IFN-gamma ELISPOT assay using splenocytes from C57BL/6 mice recovered from C. muridarum infection." "To evaluate whether the three immunodominant Chlamydia protein Ags were also able to...
Source: Women's Health Weekly (2009-04-02)
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