Women's Health Weekly
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Breast Cancer
Research in the area of breast cancer reported from J. Shen and colleagues
April 9th, 2009
According to recent research published in the International Journal of Cancer, "MicroRNA (miRNA) plays an important role in tumorigenesis, but whether miRNA is a cancer predisposition factor or not is still unknown. Considering the fact that miRNA regulates a number of tumor suppressor genes (TSGs) and oncogenes, genetic variations in miRNA genes could affect the levels of expression of TSGs or oncogenes and, thereby, cancer risk." "To test this hypothesis, we screened genetic variants in 17 selected miRNA genes, which are predicted to regulate key breast cancer genes, in 42 patients with familial breast cancer. Seven novel genetic variants were observed in 7...
Source: Women's Health Weekly (2009-04-09)
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