Women's Health Weekly
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Breast Cancer
Research on breast cancer detailed by scientists at College of Medicine
April 9th, 2009
"Clinical and experimental evidence indicates that tumor-associated macrophages (TAMs) promote malignant progression. in breast cancer, TAMs enhance tumor angiogenesis, tumor cell invasion, matrix remodeling, and immune suppression against the tumor. In this study, we examined late-stage mammary tumors from a transgenic mouse model of breast cancer," scientists in the United States report. "We used flow cytometry under conditions that minimized gene expression changes to isolate a rigorously defined TAM population previously shown to be associated with invasive carcinoma cells. The gene expression signature of this population was compared with a similar population...
Source: Women's Health Weekly (2009-04-09)
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