Women's Health Weekly
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Breast Cancer
Researchers from Nanjing Medical University detail findings in breast cancer
April 9th, 2009
According to recent research from Nanjing, People's Republic of China, "Small, noncoding RNA molecules, called microRNAs (miRNAs), are thought to function as either tumor suppressors or oncogenes. Common single, nucleotide polymorphisms (SNPs) in miRNAs may change their property through altering miRNA expression and/or maturation, and thus they may have an effect on thousands of target mRNAs, resulting in diverse functional consequences." "However, it remains largely unknown whether miRNA SNPs may alter cancer susceptibility. We evaluated the associations of selected four SNPs (rs2910164, rs2292832, rs11614913, and rs3746444) in pre-miRNAs (hsa-mir-146a, hsa-mir-149,...
Source: Women's Health Weekly (2009-04-09)
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