Women's Health Weekly
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Breast Cancer
Scientists at Osaka University, Medical Department discuss research in breast cancer
April 9th, 2009
According to a study from Suita, Japan, "Centrosome aberration in number and/or size is reportedly often observed in human breast cancer. The aim of this study was to investigate the relationship between centrosome aberration and chromosomal instability as well as the expression of centrosome regulators such as BRCA1, Aurora-A, and p53." "Centrosome aberration in number and size was determined immunohistochemically using the anti-gamma-tubulin antibody, and chromosomal instability was evaluated by fluorescence in situ hybridization analysis of chromosomes 1, 11, and 17 in paraffin sections from 50 human breast cancers. Immunohistochemical examination of BRCA1, Aurora-A,...
Source: Women's Health Weekly (2009-04-09)
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