Women's Health Weekly
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Breast Cancer
New findings reported from K.L. Ostrow and co-authors describe advances in breast cancer
April 16th, 2009
According to recent research from the United States, "Aberrant promoter hypermethylation of several known or putative tumor suppressor genes occurs frequently during the pathogenesis of various cancers including breast cancer. Many epigenetically inactivated genes involved in breast cancer development remain to be identified." "Therefore, in this study we used a pharmacologic unmasking approach in breast cancer cell lines with 5-aza-2'-deoxycytidine (5-aza-dC) followed by microarray expression analysis to identify epigenetically inactivated genes in breast cancer. Breast cancer cell lines were treated with 5-aza-dC followed by microarray analysis to identify...
Source: Women's Health Weekly (2009-04-16)
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