Women's Health Weekly
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Breast Cancer
Research from C. Schem and co-authors provides new data about breast cancer
April 16th, 2009
According to recent research from Kiel, Germany, "Sentinel lymph node (SN) biopsy is part of the staging procedure in breast cancer patients. In this study, we compared an intraoperative tool named one-step nucleic acid amplification (OSNA) to our routine histological investigation." "OSNA consists of a short homogenization step followed by amplification of cytokeratin (CK) 19 mRNA directly from the lysate. To evaluate the performance of OSNA in comparison to histology, analysis of 343 axillary lymph nodes (ALN) from 93 breast cancer patients was performed with both methods. Discordant samples were subjected to other methods. If these tests supported the OSNA results,...
Source: Women's Health Weekly (2009-04-16)
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