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Women's Health Weekly

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Breast Cancer



Researchers' work from University of Edinburgh focuses on breast cancer



April 16th, 2009

According to a study from Scotland, "The expression and activation of the Ras/Raf-1/mitogen-activated protein kinase (MAPK) pathway plays an important role in the development and progression of cancer, and may influence response to treatments such as tamoxifen and chemotherapy. In this study we investigated whether the expression and activation of the key components of this pathway influenced clinical outcome, to test the hypothesis that activation of the MAPK pathway drives resistance to tamoxifen and chemotherapy in women with breast cancer."

"Breast tumors from patients at the Glasgow Royal Infirmary and others treated within the BR9601 trial were analyzed for...


Source: Women's Health Weekly (2009-04-16)

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