Women's Health Weekly
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Breast Cancer
New breast cancer findings from University Hospital described
April 23rd, 2009
"BAG-1 is a multifunctional anti-apoptotic gene with four isoforms, and different BAG-1 isoforms have different antiapoptotic functions. In this study, we transfected BAG-1 isoforms into the human breast cancer cell lines Hs578T (ER negative) and MCF-7 (ER positive) to study their effect on apoptosis with or without estrogens," scientists writing in the journal Acta Pharmacologica Sinica report. "The constructed recombinant expression vectors carrying individual BAG-1 isoforms was used to transfect human breast cancer cell lines Hs578T (ER negative) and MCF-7 (ER positive). After stable cell lines were made, a variety of apoptosis-inducing agents, including...
Source: Women's Health Weekly (2009-04-23)
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