Women's Health Weekly
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Breast Cancer
Research from M. Hirschfeld and colleagues provide new insights into breast cancer
April 23rd, 2009
According to a study from Freiburg, Germany, "Hypoxia is known to induce the transcriptional activation of pathways involved in angiogenesis, growth factor signaling, and tissue invasion and is therefore a potential key regulator of tumor growth. Cyr61 (cysteine rich 61) is a secreted matricellular protein with proangiogenic capabilities and is transcriptionally induced under hypoxic conditions." "High expression levels of Cyr61 were already detected in various cancer types and linked to tumor progression and advanced stages in breast cancer. Besides hypoxia, there is some evidence that posttranscriptional pre-mRNA processing could be involved in the regulation of Cyr61...
Source: Women's Health Weekly (2009-04-23)
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