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Women's Health Weekly

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Breast Cancer



Research from Pfizer Inc. provides new data about breast cancer



April 23rd, 2009

According to recent research published in the journal Analytical Chemistry, "In the present study, capillary liquid chromatography (LC) nano electrospray ionization quadruple time-of flight (nano-EST-Q-TOF) mass spectrometry was utilized to identify unique proteotypic peptides for liquid chromatograpy-tandem mass spectrometry (LC-MS/MS) mediated breast cancer resistance protein (BCRP/ABCG2) and bile salt export pump (BSEP/ABCG11) quantification, using insect membrane vesicles overexpressing the proteins. The lower limit of quantification was established to be 31.25 pM and 125 nM for BCRP/ABCG2 and BSEP/ABCG11, respectively."

"The linearity of standard curves was...


Source: Women's Health Weekly (2009-04-23)

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