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Women's Health Weekly

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Breast Cancer



Scientists at Mayo Clinic target breast cancer



April 23rd, 2009

"Nanoparticle albumin-bound (nab)-paclitaxel has better efficacy and practically eliminates the risk of hypersensitivity reactions associated with solvent-based paclitaxel. We studied weekly nab-paclitaxel and gemcitabine combination in an open-label one-stage, phase II trial in patients with previously untreated metastatic breast cancer (MBC)," scientists writing in the journal Annals of Oncology report.

"Nab-paclitaxel (125 mg/m(2)) and gemcitabine (1000 mg/m(2)) were administered on days 1 and 8 of a 21-day cycle until disease progression. Fifty patients were enrolled. Forty (80%) had visceral organ involvement and 30 (60%) had >= 3 sites of metastases....


Source: Women's Health Weekly (2009-04-23)

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