Women's Health Weekly
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Breast Cancer
Studies from Queen's University in the area of breast cancer published
April 23rd, 2009
"Breast cancer 1 (BRCA1) was initially identified as one of the genes conferring genetic predisposition to both breast and ovarian cancer. One of the interesting aspects of BRCA1-linked cancers is the observed specificity for estrogen-responsive tissues such as breast and ovary," investigators in North Ireland report. "Recent advances in our understanding of BRCA1-linked breast cancers have revealed a complex relationship between BRCA1 and estrogen receptor alpha (ER alpha) signaling. Estrogen stimulation increases expression of BRCA1 at the mRNA and protein level and conversely BRCA1 functions to both induce ER alpha mRNA expression and act as a negative regulator of...
Source: Women's Health Weekly (2009-04-23)
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