Women's Health Weekly
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Breast Cancer
Study data from Indiana University provide new insights into breast cancer
April 23rd, 2009
According to recent research from the United States, "Quantitative profiling of glycans with different structures appears essential for a better understanding of the cellular adhesion phenomena associated with malignant transformation and the underlying aberrant glycosylation of cancer cells." "Using the recently developed glycomic techniques and mass-spectrometric measurements, we compare the N-linked and O-linked oligosaccharide profiles for different breast cancer cell lines with those of normal epithelial cells. Statistically significant differences in certain neutral, sialylated and fucosylated structures are readily discerned through quantitative measurements,...
Source: Women's Health Weekly (2009-04-23)
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