Women's Health Weekly
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Breast Cancer
Investigators at Technical University release new data on breast cancer
April 30th, 2009
According to recent research published in the International Journal of Oncology, "The ability of aspirin to trigger apoptosis in cancer cells is well known and is consistent with the clinical and epidemiological evidence on its chemopreventive effects in curtailing epithelial cancers, including breast cancer. We hypothesized that the anticancer effects of aspirin may involve acetylation of the tumor suppressor protein p53, a known regulator of apoptosis." "In the present study, we determined if aspirin at the physiologically achievable concentration of 100 mc M acetylates p53 and modulates the expression of p21(CIP1), a protein involved in cell cycle arrest, and...
Source: Women's Health Weekly (2009-04-30)
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