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Women's Health Weekly

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Emory University



Exposure to valproate during pregnancy can impair a child's cognitive development



April 30th, 2009

Three-year-olds whose mothers took the antiepileptic drug valproate during pregnancy had average IQs six to nine points lower than children exposed to three other antiepileptic drugs, a landmark multi-center study has found.

The study's authors say that women of childbearing age should avoid valproate as a first choice drug for the treatment of epilepsy. The results are published in the April 16, 2009, issue of the New England Journal of Medicine.

The Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) study is following more than 300 children born to women with epilepsy between 1999 and 2004. Investigators at 25 epilepsy centers in the United...


Source: Women's Health Weekly (2009-04-30)

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