Women's Health Weekly
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Breast Cancer
Research on breast cancer reported by scientists at Yonsei University
April 30th, 2009
"In breast cancer, changes of gene copy number were analyzed by cDNA microarray-based comparative genome hybridization using post-treatment archived tissues. Genomic DNA was extracted from 45 surgical specimens after chemotherapy," investigators in Seoul, South Korea report. "Informative genes were selected by t-test and were statistically validated by prediction analysis using support vector machine in R package. Fluorescence in situ hybridization and quantitative PCR were performed for validation. We developed three clinical models: comparing good vs. poor prognosis (1), comparing good vs. poor prognosis among poor responders (11) and among good responders (III). 158...
Source: Women's Health Weekly (2009-04-30)
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