Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Scientists at Duke University release new data on breast cancer
April 30th, 2009
"Dysregulation of MAL (myelin and lymphocyte protein) has been implicated in several malignancies including esophageal, ovarian, and cervical cancers. The MAL protein functions In apical transport in polarized epithelial cells; therefore, Its disruption may lead to loss of organized polarity characteristic of most solid malignancies," scientists in the United States report. "Bisulfite sequencing of the MAL promoter CpG Island revealed hypermethylation In breast cancer cell lines and 69% of primary tumors analyzed compared with normal breast epithelial cells. Differential methylation between normal and cancer DNA was confined to the proximal promoter region. In a subset...
Source: Women's Health Weekly (2009-04-30)
|
