Women's Health Weekly
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Breast Cancer
Studies from K. Mccarthy and co-researchers in the area of breast cancer published
April 30th, 2009
"Vitamin D has anti-proliferative and proapoptotic effects on several cell types, including breast cancer cells. There have been no studies quantifying the expression of the enzyme 25-hydroxyvitamin D-1-alpha-hydroxylase (1 alpha OHase), which converts 25-hydroxyvitamin D to its active metabolite, in breast tissue," researchers in the United Kingdom report. "We performed real-time RT-PCR to quantity 1 alpha OHase and vitamin D receptor (VDR) mRNA in samples of breast cancer, adjacent non-cancerous tissue and normal breast tissue. 1 alpha OHase and VDR mRNA were universally expressed, however, 1 alpha OHase expression was significantly down-regulated in adjacent...
Source: Women's Health Weekly (2009-04-30)
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