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Women's Health Weekly

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Breast Cancer



Data on breast cancer described by researchers at University of British Columbia



April 30th, 2009

"The role of somatostatin (SST) and epidermal growth factor (EGF) in breast cancer is undisputed: however, the molecular mechanisms underlying their antiproliferative or proliferative effects are not well understood. We initially confirmed that breast turnout tissues express all five somatostatin receptors (SSTR1-5) and four epidermal growth factor receptors (ErbB1-4)," researchers in Vancouver, Canada report.

"Subsequently, to gain insight into the function of SSTRs and ErbBs in oestrogen receptor (ER)-positive (MCF-7) or ER alpha-negative (MDA-MB-231) breast cancer cells, we defined SSTR1, SSTR5 and ErbB1 mRNA and protein expression in these two tumour cell lines....


Source: Women's Health Weekly (2009-04-30)

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