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Women's Health Weekly

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Breast Cancer



Research from H. Shen and co-authors in the area of breast cancer published



May 7th, 2009

According to recent research published in the journal Molecular Biology Reports, "The recent report highlighted a significant association between signal transducer and activator of transcription 3 (STAT3) and Snail and LIV-1 (SLC39A6 or ZIP6), the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. LIV-1 is a downstream target of STAT3, both in zebrafish and mammalian cells and provides control over epithelial-mesenchymal transition (EMT)."

"Crucially, these observations link LIV-1, previously demonstrated to be associated with lymph node metastasis in breast cancer, to genes with a proven role in development. A putative role of...


Source: Women's Health Weekly (2009-05-07)

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