Women's Health Weekly
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Breast Cancer
Research from M.M. Gaudet and co-researchers yields new findings on breast cancer
May 7th, 2009
According to a study from the United States, "Genetic variation in SIPA1, signal-induced proliferation-associated gene 1, has been proposed to be associated with aggressive breast tumor characteristics related to metastasis and worse prognosis in humans and rodents. To test this hypothesis, we genotyped 3 single nucleotide polymorphisms (SNP) located at -3092 (A <G, rs931127), exon 3-135 (C >T, rs3741378), and exon 14 + 14 (C >T, rs746429), and examined them in relation to breast cancer risk and overall survival, stratified by tumor characteristics in 2 independent case-control studies conducted in Poland (1,995 cases, 2,296 controls) and in Britain (2,142 cases, 2,257...
Source: Women's Health Weekly (2009-05-07)
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