Women's Health Weekly
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Breast Cancer
Research from University of Zagreb yields new data on breast cancer
May 7th, 2009
"Aims and background. Recent publications of breast cancer classification based on gene expression profile analyses indicate that medullary breast carcinomas (MBC) may be considered part of the basal-like carcinoma spectrum made lip of ER-negative, PR- negative and HER-2-negative cells (''triple-negative phenotype'')," investigators in Zagreb, Croatia report. "On the other hand, there are also data showing that a proportion of MBC and atypical MBC (AMBC) is ER, PR and/or HER-2 positive. Therefore, we have decided to immunohistochemically analyze ER, PR, HER-2 and basal/myoepithelial markers CK 5/6, p63 and EGFR expression in our archival paraffin-embedded MBC and AMBC...
Source: Women's Health Weekly (2009-05-07)
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