Women's Health Weekly
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Breast Cancer
Research reports from J.J. Fu and co-authors provide new insights into breast cancer
May 7th, 2009
According to recent research from Shanghai, People's Republic of China, "Androgen receptor (AR) plays a critical role in development and maintenance of male reproductive functions and the etiology of prostate cancer. As a ligand-regulated transcription factor, identification and characterization of AR coregulators are essential for understanding the molecular mechanisms underlying its diverse biological functions." "Here we reported the identification of a novel AR coactivator, deleted in breast cancer 1 (DBC1), through a biochemical approach. DBC1 interacts with AR in a ligand-stimulated manner and facilitates AR transcriptional activation in transfected cells as well...
Source: Women's Health Weekly (2009-05-07)
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