Women's Health Weekly
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Breast Cancer
Scientists at Shandong University publish new data on breast cancer
May 7th, 2009
"beta-arrestins, a family of regulatory and scaffold proteins, are well-known negative regulators of G-protein-coupled receptors (GPCRs) including opioid receptors. Recent studies have shown that beta-arrestin2 plays a potential role in inhibiting cell death," scientists writing in the journal Neoplasma report. "It has been reported that opioids such as morphine induce cell death at high concentrations (>500 mc M for 24 hours), which is similar to morphine plasma concentrations in cancer patients receiving chronic morphine treatment for pain relievers. However, the role of beta-arrestin2 in opioid-induced cell death remains to be elucidated. We report here...
Source: Women's Health Weekly (2009-05-07)
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