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Women's Health Weekly

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Cancer



Reports outline cancer study findings from Rutgers University



May 7th, 2009

"Numerous preclinical, epidemiologic, and clinical studies have suggested the benefits of vitamin D and its analogues for the prevention and treatment of cancer. However, the hypercalcemic effects have limited the use of 1 alpha,25(OH)(2)D-3, the hormonally active form of vitamin D. To identify vitamin D analogues with better efficacy and low toxicity, we have tested >60novel Gemini vitamin D analogues with a unique structure of two side chains for growth inhibition of breast cancer cells," scientists in the United States report.

"Our initial studies found that some Gemini analogues are 5-15 times more active than 1 alpha,25(OH)(2)D-3 in growth inhibition assay. In...


Source: Women's Health Weekly (2009-05-07)

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