Women's Health Weekly
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Cancer
Research by F. Almulla and colleagues in cancer provides new insights
May 21st, 2009
"BRCA1 gene mutations have been extensively studied in relation to breast and ovarian cancer susceptibility. Various genotype-phenotype correlation attempts have yielded important data pertaining to the consequences of BRCA1 mutations," scientists writing in the Journal of Clinical Pathology report. "However, little is known about the effects of recurrent BRCA mutations on expressivity and the age of onset of cancer in a population. This study addresses whether different exon mutations have variable expressivity especially in relation to the age of onset of breast cancer. Using a step-wise systematic approach, culminating in the sequencing of all BRCA1 and BRCA2...
Source: Women's Health Weekly (2009-05-21)
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