Women's Health Weekly
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Cancer
Research from Radboud University in the area of cancer published
May 21st, 2009
According to recent research published in the journal Clinical & Experimental Metastasis, "For cancer progression and metastatic dissemination, cancer cells migrate and penetrate through extracellular tissues. Cancer invasion is frequently facilitated by proteolytic processing of components of the extracellular matrix (ECM)." "The cellular regions mediating proteolysis are diverse and depend upon the physical structure, composition, and dimensionality of the ECM contacted by the cell surface. Cancer cells migrating across 2D substrate contain proteolytic structures such as lamellipodia, invadopodia, and the trailing edge. Likewise, invasive mesenchymal migration...
Source: Women's Health Weekly (2009-05-21)
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