Thrombosis
New data from R.D. Seheult et al illuminate research in hypertension
Published in Women's Health Weekly, May 28th, 2009
According to recent research published in the journal Respiratory Physiology & Neurobiology, "Hypoxic pulmonary vasoconstriction in response to high altitude ascent may contribute to decreased exercise capacity. Endothelin receptor antagonists reduce pulmonary artery pressure and improve exercise capacity in patients with pulmonary arterial hypertension, but their effects on exercise capacity at attitude are unknown."
"We studied the efficacy of bosentan started 5 days prior to ascent on exercise capacity and pulmonary artery systolic pressure (PASP) at 3800 m altitude. Eight healthy subjects completed a double-blinded, randomized, placebo-controlled, crossover...
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