Women's Health Weekly
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Breast Cancer
Research on breast cancer described by scientists at University of Sheffield
May 28th, 2009
"Recent large-scale studies have been successful in identifying common, low-penetrance variants associated with common cancers. One such variant in the caspase-8 (CASPS) gene, D302H (rs1045485), has been confirmed to be associated with breast cancer risk, although the functional effect of this polymorphism (if any) is not yet clear," investigators in Sheffield, the United Kingdom report. "In order to further map the CASP8 gene with respect to breast cancer susceptibility, we performed extensive haplotype analyses using single nucleotide polymorphisms (SNP) chosen to tag all common variations in the gene (tSNP). We used a staged study design based on 3,200 breast cancer...
Source: Women's Health Weekly (2009-05-28)
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