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Women's Health Weekly

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Breast Cancer



Studies from Federal University have provided new data on breast cancer



May 28th, 2009

According to recent research from Curitiba, Brazil, "ADAM33 protein is a member of the family of transmembrane glycoproteins composed of multidomains. ADAM family members have different activities, such as proteolysis and adhesion, making them good candidates to mediate the extracellular matrix remodelling and changes in cellular adhesion that characterise certain pathologies and cancer development."

"It was reported that one family member, ADAM23, is down-regulated by promoter hypermethylation. This seems to correlate with tumour progression and metastasis in breast cancer. In this study, we explored the involvement of ADAM33, another ADAM family member, in breast...


Source: Women's Health Weekly (2009-05-28)

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