Women's Health Weekly
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Breast Cancer
Study data from University of Nottingham provide new insights into breast cancer
May 28th, 2009
"Triple-negative (TN; estrogen receptor, progesterone receptor, and HER-2 negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome and lack the benefit of targeted therapy. It is widely perceived that BLBC and TN tumors are synonymous and BLBC can be defined using a TN definition without the need for the expression of basal markers," scientists in Nottingham, the United Kingdom report. "We have used two well-defined cohorts of breast cancers with a large panel of biomarkers, BRCA1 mutation status, and follow-up data to compare the clinicopathologic and immunohistochemical features of TN tumors expressing one or more of the specific basal...
Source: Women's Health Weekly (2009-05-28)
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