Women's Health Weekly
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Cancer
New cancer research reported from University of Miami
May 28th, 2009
"Extracellular matrix (ECM) molecules modify gene expression through attachment-dependent (focal adhesion-related) Integrin receptor signaling. It was previously unknown whether the same molecules acting as soluble peptides could generate signal cascades without the associated mechanical anchoring, a condition that may be encountered during matrix remodeling and degradation and relevant to invasion and metastatic processes," scientists writing in the journal Molecular Cancer Research report. "In the current study, the role of ECM ligand-regulated gene expression through this attachment-independent process was examined. It was observed that fibronectin, laminin,...
Source: Women's Health Weekly (2009-05-28)
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