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Women's Health Weekly

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Cancer Gene Therapy



Data on cancer gene therapy published by J.A. Westwood and colleagues



May 28th, 2009

"In this study we aimed to determine the suitability of the Lewis-Y carbohydrate antigen as a target for immunotherapy using genetically redirected T cells, Using the 3S193 monoclonal antibody and immunohistochemistry, Lewis-Y was found to be expressed on a range of tumors including 42% squamous cell lung carcinoma, 80% lung adenocarcinoma. 25% ovarian carcinoma, and 25% colorectal adenocarcinoma. Expression levels varied from low to intense on between 1% and 90% of tumor cells," scientists writing in the Journal of Immunotherapy report.

"Lewis-(Y) was also found in soluble form in sera from both normal donors and cancer patients using a newly developed...


Source: Women's Health Weekly (2009-05-28)

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