Women's Health Weekly
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Breast Cancer
Scientists at University of Colorado, Medical Department discuss research in breast cancer
June 4th, 2009
According to recent research published in the journal Cell Cycle, "The anti-diabetic drug metformin reduces human cancer incidence and improves the survival of cancer patients, including those with breast cancer. We studied the activity of metformin against diverse molecular subtypes of breast cancer cell lines in vitro." "Metformin showed biological activity against all estrogen receptor (ER) positive and negative, erbB2 normal and abnormal breast cancer cell lines tested. It inhibited cellular proliferation, reduced colony formation and caused partial cell cycle arrest at the G(1) checkpoint. Metformin did not induce apoptosis (as measured by DNA fragmentation...
Source: Women's Health Weekly (2009-06-04)
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